TY  - BOOK
AU  - Delyagina, Evgenya
PY  - 2016
DA  - 2016//
TI  - Magnetic nanoparticle-based gene delivery: mechanisms and clinical perspectives = Magnetische Nanopartikel-basierter Gentransfer : Mechanismen und Klinische Perspektiven
PB  - Universität Rostock
CY  - Rostock
AB  - The development of safe and efficient gene delivery systems is the key to the overall success of gene therapy. This work introduced a MNP-based nonviral gene delivery approach for transfection in clinically relevant cells. Moreover, the in vitro mechanism studies could explained the beneficial properties of the proposed carrier design. This work demonstrated, that proposed system could efficiently and safely transfect human bone marrow derived mesenchymal stem cells. Additionaly, the clinical perspectives of MNP-based gene therapy were discussed and evaluated in this dissertation.<eng>
UR  - http://rosdok.uni-rostock.de/resolve/urn/urn:nbn:de:gbv:28-diss2017-0038-4
LA  - English
N1  - submitted by Evgenya Delyagina from Reinach BL, Switzerland
ID  - 882994220
ER  -