TY - BOOK AU - Mörke, Caroline PY - 2016 DA - 2016// TI - Caveolae-mediated phagocytosis of biomaterial surface structures by human osteoblasts PB - Universität Rostock CY - Rostock AB - Cells are sensitive to their underlying topography, which evoke large ranges of cell responses. The work describes an attempted caveolae-mediated phagocytosis of the surface-fixed micro-pillars by human MG-63 osteoblastic cells. This attempt to phagocytize the elevations of the Ti surface results in higher energy requirements for the cells and finally to impaired osteoblast function. Similar cell responses were observed for the osteoblasts treated with micro-particles as phagocytosis trigger and osteoblasts growing on stochastic rough Ti surfaces, commercially used as implant surfaces. UR - http://rosdok.uni-rostock.de/resolve/urn/urn:nbn:de:gbv:28-diss2016-0099-5 LA - English N1 - vorgelegt von Caroline Mörke ID - 865832447 ER -