TY  - BOOK
AU  - Rudolf, Henrik
PY  - 2015
DA  - 2015//
TI  - Analyzing gene expression data with linear mixed models: applications to variable pool sizes and biomarkers
PB  - Universität Rostock
CY  - Rostock
AB  - This work is about the design and statistical analysis of gene expression experiments with variable pool sizes. Conditions for unbiased contrasts in such experiments were derived. They were analyzed with linear mixed models, introducing a new type of variance component that accounts for unequal shares of individual samples in common pools. The relevance of this blending error variance was then investigated for four experimental data sets from different species. Finally a biomarker search for hygienic behavior in Apis mellifera workers was conducted, using nerve tissue gene expression data.<eng>
UR  - http://rosdok.uni-rostock.de/resolve/urn/urn:nbn:de:gbv:28-diss2016-0062-1
LA  - English
N1  - submitted by: Henrik Rudolf from Rostock
ID  - 862648602
ER  -