TY - BOOK AU - Ludwig, Marion PY - 2014 DA - 2014// TI - regenerative potential of the CD117+AT2R stimulated cell population in vitro and in vivo: = Das regenerative Potential der CD117+AT2R stimulierten Zellpopulation in vitro und in vivo AB - Regarding innovative therapeutical approaches for cardiac regeneration, we thoroughly investigated CD117+ and CD117+AT2R stimulated murine bone marrow stem cells. Electrophysiological measurements and in vitro results indicated the differentiation into an endothelial-like phenotype excluding a previously discussed development into cardiomyocytes. Cell implantation into infarcted murine heart provoked a significant improvement of cardiac function. AT2R triggered effects were not significantly different and should be analyzed in interplay with its opposing receptor AT1. UR - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2015-0146-3 UR - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2015-0146-3&pdf UR - http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2015-0146-3 LA - English N1 - submitted by : Marion Ludwig ID - 833973207 ER -