TY - BOOK AU - Du, Yang PY - 2014 DA - 2014// TI - Functional characterization and annotation of trait-associated genomic regions by transcriptome analysis AB - In this work, two novel implementations have been presented, which could assist in the design and data analysis of high-throughput genomic experiments. An efficient and flexible tiling probe selection pipeline utilizing the penalized uniqueness score has been implemented, which could be employed in the design of various types and scales of genome tiling task. A novel hidden semi-Markov model (HSMM) implementation is made available within the Bioconductor project, which provides a unified interface for segmenting genomic data in a wide range of research subjects. UR - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0196-0 UR - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0196-0&pdf UR - http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2014-0196-0 LA - English N1 - vorgelegt von Yang Du ID - 812372174 ER -