TY  - BOOK
AU  - Fritz, Ria
PY  - 2013
DA  - 2013//
TI  - Cloud point extraction of proteins and characterisation by liquid chromatography and mass spectrometry
AB  - Using the non-ionic detergent Triton X-114, hydrophobic proteins and possible Alzheimer's disease related amyloid beta 42 oligomer species were extracted from mouse brain tissue. Extracted proteins were identified following SDS PAGE by LC-MS/MS data analysis and characterised based on the relation of grand average hydropathicity index (GRAVY) to extraction phase, cellular location and function. A SEC-MS method was developed with the prospective aim of providing simultaneous detection of multiple oligomeric Abeta 42 species using characteristic charge state distributions.
UR  - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0113-4
UR  - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0113-4&pdf
UR  - http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2014-0113-4
LA  - English
N1  - vorgelegt von Ria Fritz
ID  - 793167361
ER  -