TY - BOOK AU - Ostrovskyi, Dmytro PY - 2012 DA - 2012// TI - Routes to polysubstituted and condensed pyridines and diazines - utilization of 1,3-bielectrophiles and transition metal-based catalysis in ring synthesis/modification AB - The present work aimed to study the potential of well-known synthetic strategies for the synthesis of imidazo[4,5-b]pyridine-derived (or 1-desazapurine-derived), purine-derived and benzimidazole-derived moieties and their modifications. This includes [3+3] cyclocondensations, inverse electron-demand Diels-Alder reaction, intramolecular palladium-catalyzed arylation. In addition, unprecedented method of synthesis of 4-trifluoromethylpyridines was developed, including scope limitation and theoretical mechanistic studies with DFT methods. UR - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0008-6 UR - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0008-6&pdf UR - http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2013-0008-6 LA - English N1 - vorgelegt von Dmytro Ostrovskyi ID - 734092741 ER -