TY  - BOOK
AU  - Wang, Weiwei
PY  - 2010
DA  - 2010//
TI  - Polymervermittelter Gentransfer für die Therapie mit adulten Stammzellen
AB  - Polymer mediated gene delivery was studied and utilized in adult stem cell therapy. The gene expression of human mesenchymal stem cells (MSCs) could be significantly enhanced by polyethylenimine (PEI) mediated gene delivery. The tumor cell growth could be effectively inhibited both in vitro and in vivo by delivering antisense oligonucleotide with non-viral method. Furthermore, gene activated substrate (GAS) prepared in this study could allow localized gene delivery, sustained gene release, high transfection efficiency, low cytotoxicity and high potential for stem cell recruitment.
UR  - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2011-0070-9
UR  - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2011-0070-9&pdf
UR  - http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2011-0070-9
UR  - http://d-nb.info/1014239990/34
UR  - http://rosdok.uni-rostock.de/file/rosdok_derivate_000000004608/Dissertation_Wang_2011.pdf
LA  - English
N1  - vorgelegt von Weiwei Wang
ID  - 658204726
ER  -