TY - BOOK AU - Furlani, Dario PY - 2009 DA - 2009// TI - Stem cells therapy after myocardial infarction: direct application or drug-mediated recruitment? AB - Heart failure after myocardial infarction is the first cause of death in west countries. Stem cells could ameliorate this process by inducing neoangiogenesis and/or cardiac myocytes regeneration. This thesis focused on two crucial topics: drug mediated stem cell recruitment and safety issues related to stem cell transplantation. The effects of stem cells mobilization and cardiac recruitment induced by Erythropoietin through the activation of SDF-1/CXCR4 axis were examined. The safety of mesenchymal stem cells intraarterial transplantation and ex-vivo expansion were investigated. UR - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2010-0045-6 UR - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2010-0045-6&pdf UR - http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2010-0045-6 UR - http://rosdok.uni-rostock.de/metadata/rosdok_disshab_000000000412 UR - http://d-nb.info/1003037283/34 LA - English N1 - submitted by Dario Furlani ID - 622388339 ER -