TY  - BOOK
AU  - Wang, Xinchao
PY  - 2009
DA  - 2009//
TI  - Streptamer technology allows to isolate leukemia antigen-specific CD8+ T cells
AB  - In this work we investigated whether streptamer technology could purify WT1-specific CD8+ T cells, what is important for the development of adoptive immunotherapy. Sample from HLA/A2+ HDs were identified and selected by streptamer. The function of selected CD8+ T cells was identified by the staining of phenotypic markers. The results showed that streptamer permits the detection and selection of WT1-specific CD8+ T cells in the PBMCs from HDs. The naïve function of selected CD8+ T cells was preserved and most selected CD8+ T cells demonstrated an effector T cell immunophenotype.
UR  - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0196-0
UR  - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0196-0&pdf
UR  - http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2009-0196-0
UR  - http://rosdok.uni-rostock.de/file/rosdok_derivate_000000004099/Dissertation_Wang_2009.pdf
UR  - http://d-nb.info/99976232X/34
LA  - English
N1  - presented by Xinchao Wang
ID  - 613868986
ER  -