TY  - BOOK
AU  - Brennführer, Anne
PY  - 2008
DA  - 2008//
TI  - Palladium/di-1-adamantyl-n-butylphosphine-catalyzed carbonylation reactions
AB  - Within this thesis several homogeneous palladium-catalyzed carbonylation reactions in the presence of carbon monoxide were investigated. In the course of our studies, the superior performance of the catalyst system palladium acetate/di-1-adamantyl-n-butylphosphine (cataCXium® A) in comparison to established palladium catalysts was demonstrated for both reductive carbonylations and alkoxycarbonylations of aryl and vinyl bromides. Hence, a variety of (hetero)aromatic aldehydes and carboxylic acid derivatives (esters, amides, acids) were successfully synthesized, among them novel biologically interesting indolylmaleimides. Furthermore, an efficient method for the synthesis of non-steroidal anti-inflammatory drugs such as ketoprofen and suprofen was developed.
UR  - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0110-5
UR  - http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0110-5&pdf
UR  - http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2009-0110-5
LA  - English
N1  - Anne Brennführer
ID  - 604071264
ER  -