TY - BOOK AU - Ren, Yanru PY - 2025 DA - 2025// TI - Cytocompatibility and biocompatibility approaches with analysis of the in vivo immune responses of collagen-based and synthetic materials for bone regeneration PB - Universität Rostock CY - Germany; Rostock AB - This study aims to clarify the immunomodulatory role of these biomaterials in relation to tissue regeneration. Evaluate the cellular and biocompatibility properties of synthetic bone substitutes with metal ions and collagen-based barrier membranes. Assessments used subcutaneous or calvarial implantation models, focusing on macrophage-driven inflammatory patterns and tissue regeneration. Aligned with 3R principles, it also investigates jellyfish collagen to optimize in vitro cell culture and improve the accuracy of cellular compatibility predictions. UR - https://purl.uni-rostock.de/rosdok/id00005766 UR - https://doi.org/10.18453/rosdok_id00005766 DO - 10.18453/rosdok_id00005766 LA - English N1 - vorgelegt von Yanru Ren ID - 1982221771 ER -