TY - BOOK AU - Baum, Christoph Ferdinand PY - 2024 DA - 2024// TI - Function of energy-converting hydrogenases and transhydrogenase in the metabolism of the thermophilic acetogenic bacterium Thermoanaerobacter kivui PB - Universität Rostock CY - Rostock AB - Electron transfer between H₂, ferredoxin, NADH and NADPH is essential for the redox balance and energy metabolism in Thermoanaerobacter kivui. The hydrogenases Ech1 and Ech2 are important for energy conservation on H₂/CO₂ or CO. Deletion of Ech2 impaired growth on pyruvate and CO, but not on sugars. Ech1 could not be completely deleted, but downregulation led to similar effects. Deletion of the electron-bifurcating transhydrogenase NfnAB interfered with growth on all substrates, and mixotrophic growth studies with glucose showed H₂-induced growth inhibition. UR - https://purl.uni-rostock.de/rosdok/id00005153 UR - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00005153-9 UR - https://d-nb.info/1393157092/34 UR - https://doi.org/10.18453/rosdok_id00005153 DO - 10.18453/rosdok_id00005153 LA - English N1 - vorgelegt von Christoph Ferdinand Baum ID - 1963653858 ER -