TY - BOOK AU - Tang, Guanglin PY - 2023 DA - 2023// TI - Evaluating distress of animals in mouse models for liver fibrosis PB - Universität Rostock CY - Rostock AB - There are few studies that define which methods are appropriate to measure the severity of suffering in animals. In the first study, we showed that corticosterone elevation is an important parameter for the assessment of distress in mice. In the second study, we analyzed the diagnostic value of a distress score, burrowing activity and body weight change in animal models of liver fibrosis. In the third study, the power of single and multiple parameters to determine an early humane endpoint was analyzed. UR - https://purl.uni-rostock.de/rosdok/id00005031 UR - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00005031-6 UR - https://d-nb.info/1385075201/34 UR - https://doi.org/10.18453/rosdok_id00005031 DO - 10.18453/rosdok_id00005031 LA - English N1 - vorgelegt von Guanglin Tang ID - 1945998741 ER -