TY - BOOK AU - Hou, Hsuan-Wu PY - 2024 DA - 2024// TI - Establishing the greenhouse-production of FGF21-Transferrin in tobacco seeds and leaves for oral treatment of non-alcoholic steatosis hepatis NASH: = Etablierung der Gewächshausproduktion von FGF21-Transferrin in Tabaksamen und -blättern zur oralen Behandlung der nichtalkoholische Steatohepatitis NASH PB - Universität Rostock CY - Rostock AB - Thesis focuses on the production of a variant of the human fibroblast growth factor (FGF21) in plants. This factor is supposed to support the liver function, but has a negative impact on other organs. Hence it has to be directed directly to the liver and should be unstable to avoid its presence in other organs. An oral intake would be preferred. Plants provide an excellent platform for the production of orally applied pharmaceuticals since the cell wall protects the substance from premature degradation in the gastric system. UR - https://purl.uni-rostock.de/rosdok/id00004889 UR - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004889-6 UR - https://d-nb.info/1373150777/34 UR - https://doi.org/10.18453/rosdok_id00004889 DO - 10.18453/rosdok_id00004889 LA - English N1 - vorgelegt von Hsuan-Wu Hou ID - 1932007393 ER -