TY  - BOOK
AU  - Rinaldi, Selina
PY  - 2025
DA  - 2025//
TI  - Evaluating in vitro toxicity of flavors in alternative nicotine delivery systems utilizing different in vitro testing strategies
PB  - Universität Rostock
CY  - Rostock
AB  - The respiratory and local health effects of flavors in alternative nicotine delivery systems (ANDS) are not well understood. This dissertation aimed to develop an in vitro risk assessment strategy for ANDS flavors and identify oral nicotine pouch (ONP) ingredients. Further, the impinger method was optimized for collecting flavored aerosols. Based on the results, a tiered testing approach is advised using submerged and Air-Liquid Interface cell models. Further, standardized testing guidelines for flavoring compounds in emerging ANDS are needed for comprehensive safety assessments.<eng>
UR  - https://purl.uni-rostock.de/rosdok/id00004874
UR  - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004874-8
UR  - https://d-nb.info/1372071903/34
UR  - https://doi.org/10.18453/rosdok_id00004874
DO  - 10.18453/rosdok_id00004874
LA  - English
N1  - vorgelegt von Selina Rinaldi
ID  - 1931303371
ER  -