TY  - BOOK
AU  - Berthold, Anne
PY  - 2024
DA  - 2024//
TI  - Epigenetic studies in bovine mastitis cell models
PB  - Universität Rostock
CY  - Rostock
AB  - This study focused on histone modifications and their role in epithelial cell models MAC-T and pbMEC exposed to mastitis pathogens Escherichia coli and Staphylococcus aureus. Main insights were gained by molecular techniques, including N-ChIP-qPCR, RNA-seq, and X-ChIP-seq. Both cell types upregulated immune genes in response to pathogen contact. The findings revealed significantly different gene expression and peaks for H3K4me3 and H3K27me3 between MAC-T and pbMEC. Moreover, the genome-wide data indicated epigenetic control of upregulated genes after the Escherichia coli challenge in pbMEC.<eng>
UR  - https://purl.uni-rostock.de/rosdok/id00004844
UR  - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004844-8
UR  - https://d-nb.info/1370896042/34
UR  - https://doi.org/10.18453/rosdok_id00004844
DO  - 10.18453/rosdok_id00004844
LA  - English
N1  - vorgelegt von Anne Berthold
ID  - 1928914721
ER  -