TY - BOOK AU - Ghasemian, Khadijeh PY - 2023 DA - 2023// TI - Strategies to control mouse populations: production of species-specific contraceptive peptides in plants as oral vaccine = Strategien zur Kontrolle von Mäusepopulationen : Produktion artspezifischer kontrazeptiver Peptide in Pflanzen als oraler Impfstoff PB - Universität Rostock CY - Rostock AB - The aim of the study was to develop strategies to produce an oral contraceptive vaccine for mice in plants, in order to reduce the mouse population. The results showed that mouse-specific contraceptive peptides were successfully produced in plants. All peptides induced IgG antibodies in subcutaneously vaccinated mice. Moreover, oral delivery of the leaves expressing a fusion protein elicited systemic and mucosal cross-reactive antibodies. Observations suggest that plant-produced contraceptives have the potential to be used in the development of feeding baits to reduce the fertility of mice. UR - https://purl.uni-rostock.de/rosdok/id00004672 UR - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004672-2 UR - https://d-nb.info/1342194268/34 UR - https://doi.org/10.18453/rosdok_id00004672 DO - 10.18453/rosdok_id00004672 LA - English N1 - submitted by Khadijeh Ghasemian ID - 190217822X ER -