TY  - BOOK
AU  - Albony, Hasan
PY  - 2021
DA  - 2021//
TI  - Phosphoproteome analysis of the near-haploid cell line HAP1 reveals phosphorylation events originating from PDZ-binding kinase/T-LAK cell-originated protein kinase (PBK/TOPK)
PB  - Universität Rostock
CY  - Rostock
AB  - PBK is a serine/threonine kinase. During mitosis, PBK phosphorylates the inter-zinc finger linker sequence (TGEKP) of hundreds of C2H2 zinc finger proteins and liberates these transcription factors from the condensing chromatin. This study aimed to investigate PBK-dependent phosphorylation events by analyzing the phosphoproteome of both wild and PBK knockout HAP1 cells. The analysis identified candidates belong to DNA- and RNA binding proteins (ADNP and FUBP1) or dynamic regulators of cell organelles (MARCKS and PGRMC1).<eng>
UR  - https://purl.uni-rostock.de/rosdok/id00004478
UR  - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004478-9
UR  - https://d-nb.info/1313002321/34
UR  - https://doi.org/10.18453/rosdok_id00004478
DO  - 10.18453/rosdok_id00004478
LA  - English
N1  - vorgelegt von Hasan Albony
ID  - 1872125352
ER  -