TY  - BOOK
AU  - Lupu, Loredana-Mirela
PY  - 2022
DA  - 2022//
TI  - Elucidation of molecular recognition structures of peptides and proteins to antibodies and DNA aptamers by biosensor- mass spectrometry combination
PB  - Universität Rostock
CY  - Rostock
AB  - The PROTEX-SPR-MS method has unveiled several epitopes with promising medical applications, including an epitope peptide suitable for antibody removal in Fabry's disease. Additionally, an epitope conducive to early heart muscle injury diagnosis was identified and characterized.Furthermore, PROTEX-SPR-MS has been employed to study two distinct single-stranded DNA aptamers interacting with a tumor biomarker protein. This analysis has revealed that aptamers have remarkably similar affinity and epitope binding to antibodies, suggesting their potential utility in medical applications.<eng>
UR  - https://purl.uni-rostock.de/rosdok/id00004458
UR  - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004458-6
UR  - https://d-nb.info/1309753776/34
UR  - https://doi.org/10.18453/rosdok_id00004458
DO  - 10.18453/rosdok_id00004458
LA  - English
N1  - vorgelegt von Loredana-Mirela Lupu
ID  - 1869704800
ER  -