TY - BOOK AU - Offer, Svenja Hannah PY - 2023 DA - 2023// TI - Cellular and molecular toxicity of atmospherically aged anthropogenic and biogenic aerosols PB - Universität Rostock CY - Germany; Rostock AB - This dissertation addresses the question about the toxicological impacts of atmospherically aged biogenic and anthropogenic emissions. In simulation experiments, an anthropogenic (naphthalene) or biogenic (β-pinene) VOC precursor was aged together with a primary aerosol and comprehensively physical and chemical characterized. Using different in vitro airway model systems [BEAS-2B, A549 and a coculture of A549/EA.hy926] in an automated air-liquid interface exposure system, the cellular effects triggered by the aerosols were tested by evaluating the genomic, metabolomic and functional changes. UR - http://purl.uni-rostock.de/rosdok/id00004409 UR - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004409-8 UR - https://d-nb.info/130101673X/34 UR - https://doi.org/10.18453/rosdok_id00004409 DO - 10.18453/rosdok_id00004409 LA - English N1 - vorgelegt von Svenja Hannah Offer ID - 1857865693 ER -