TY  - BOOK
AU  - Pantzke, Jana
PY  - 2023
DA  - 2023//
TI  - Multicellular in vitro systems assessing primary and secondary genotoxicity involved in particle-driven pro-fibrotic conditions
PB  - Universität Rostock
CY  - Rostock
AB  - Since exposure to inhalable substances such as fibers or fine dusts is associated with the development of pulmonary fibrosis  various in vitro cell models capable of detecting mechanistic changes due to pollutant exposure were developed in this work. Models of different complexity were exposed to particles of various sources and investigated regarding their inflammatory, (secondary) genotoxic and fibrotic potential. The studies have shown that the models are suitable to capture mechanistic processes involved in the development of pulmonary fibrosis and thus facilitate toxicity assessment.<eng>
UR  - http://purl.uni-rostock.de/rosdok/id00004397
UR  - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004397-8
UR  - https://d-nb.info/1298674999/34
UR  - https://doi.org/10.18453/rosdok_id00004397
DO  - 10.18453/rosdok_id00004397
LA  - English
N1  - vorgelegt von Jana Pantzke
ID  - 1853934887
ER  -