TY  - BOOK
AU  - Baschung, Yannick
PY  - 2022
DA  - 2022//
TI  - Development and application of affinity-mass spectrometry to identify protein-carbohydrate interactions
PB  - Universität Rostock
CY  - Rostock
AB  - Affinity mass spectrometry using selective and pressure-enhanced proteolytic excision and extraction combined with MALDI and ESI-MS has been applied to the identification of epitope binding sites of GalNac and blood group oligosaccharides in lectins. The epitope peptides identified comprise all essential amino acids involved in carbohydrate recognition, in complete agreement with available X-ray structures. Coupling of a specific peptide glycoprobe to the gold surface of a biosensor chip was successfully employed for identification of carbohydrate epitopes and affinity measurements.<eng>
UR  - http://purl.uni-rostock.de/rosdok/id00004147
UR  - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004147-3
UR  - https://d-nb.info/1293540110/34
UR  - https://doi.org/10.18453/rosdok_id00004147
DO  - 10.18453/rosdok_id00004147
LA  - English
N1  - vorgelegt von Yannick Baschung
ID  - 1833803752
ER  -