TY - BOOK AU - Sadraddin, Haval Lutfalla PY - 2019 DA - 2019// TI - Antiarrhythmic effect of human bone marrow-dereived CD271+ mesenchymal stem cells tested in vivo using a new infarction-re-infarction mouse model PB - Universität Rostock CY - Rostock AB - This experiment showed the safety and antiarrhythmic effect of human bone marrow-derived CD271+ MSC. This was performed in immune deficient mice (Rag2-/-γc-/--mice) with electrocardiogram monitoring through Implantation of telemtry system. The induction of ventricular arrhythmias has been achieved via a permanent re-infarction through left anterior descending artery (LAD) ligation one week after a 30-minute ischemia-reperfusion. The time between 2 infarctions gave the stem cells the required period to entgraft themselves after their intramyocardial injection with the first infarction. UR - http://purl.uni-rostock.de/rosdok/id00002970 UR - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002970-5 UR - https://d-nb.info/129366278X/34 UR - https://doi.org/10.18453/rosdok_id00002970 DO - 10.18453/rosdok_id00002970 LA - English N1 - vorgelegt von Haval Lutfalla Sadraddin ID - 175043959X ER -