TY - BOOK AU - Thiele, Frauke PY - 2019 DA - 2019// TI - Optimisation of stem cell based approaches towards cardiac regeneration PB - Universität Rostock CY - Rostock AB - Aberrant behaviour of resident cells causes several illnesses. Among them, cardiovascular diseases are the leading cause of death in the western world. The human heart possesses only negligible myocardial regeneration capacity after a myocardial infarction, thus, it cannot compensate the massive cell loss self-reliantly. The thesis addresses the optimization of different cell biological approaches for enrichment of cardiac subtypes. Moreover, the thesis demonstrates different genetic manipulation strategies (DNA-, mRNA- and microRNA-based) for an efficient modulation of cell fate. UR - http://purl.uni-rostock.de/rosdok/id00002896 UR - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002896-1 UR - https://d-nb.info/1293662240/34 UR - https://doi.org/10.18453/rosdok_id00002896 DO - 10.18453/rosdok_id00002896 LA - English N1 - vorgelegt von Frauke Thiele geb. Hausburg ID - 1745155198 ER -