TY - BOOK AU - Okai, Charles Ayensu PY - 2020 DA - 2020// TI - Proteome profiling of maternal serum: a novel approach for intrauterine growth restriction screening during pregnancy PB - Universität Rostock CY - Rostock AB - Fetal growth restriction affects pregnancies leading to perinatal mortality and morbidity. Current diagnostic method is by ultrasound inspection but cannot differentiate SGA fetuses from IUGR fetuses. Maternal serum from IUGR, SGA and control pregnant women were analysed using affinity-mass spectrometry. Separation confidence reached a sensitivity of 0.90, specificity of 0.79 with an area under curve of 0.88 in receiver operator characteristics. Proteome profiling by affinity-mass spectrometry during pregnancy provides a reliable method for risk assessment of impaired development in fetuses. UR - http://purl.uni-rostock.de/rosdok/id00002801 UR - https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002801-9 UR - https://d-nb.info/1293661325/34 UR - https://doi.org/10.18453/rosdok_id00002801 DO - 10.18453/rosdok_id00002801 LA - English N1 - vorgelegt von Charles Ayensu Okai ID - 1738299295 ER -