TY  - BOOK
AU  - Herzmann, Nicole
PY  - 2017
DA  - 2017//
TI  - impact of bacteria and their cell wall components LPS and LTA on proliferation, differentiation and migration of human adipose-derived mesenchymal stem cells in vitro
PB  - Universität Rostock
CY  - Rostock
AB  - The aim of the studies was to analyze the influence of Gram-negative and -positive wound infection relevant bacteria and their cell wall components LPS and LTA on cellular processes (e.g. proliferation, osteogenic and adipogenic differentiation, NF-kappaB signaling, migration and chemotaxis) of adMCS. We could show that, the LPS-induced increase in proliferation and osteogenic differentiation of adMSC could be abolished by competitive inhibition of TLR4. The data strengthen the evidence for a role of TLR4 in the regulation of proliferation and differentiation of adMSC.<eng>
UR  - http://rosdok.uni-rostock.de/resolve/id/rosdok_disshab_0000001925
UR  - https://nbn-resolving.org/urn:nbn:de:gbv:28-diss2018-0097-1
UR  - https://d-nb.info/1293652857/34
UR  - https://doi.org/10.18453/rosdok_id00002103
DO  - 10.18453/rosdok_id00002103
LA  - English
N1  - submitted by Nicole Herzmann
ID  - 1025278135
ER  -