mechanisms and clinical perspectives = Magnetische Nanopartikel-basierter Gentransfer : Mechanismen und Klinische Perspektiven Mechanismen und Klinische Perspektiven Delyagina, Evgenya 1986- VerfasserIn aut Steinhoff, Gustav 1958- GutachterIn oth Pützer, Brigitte Maria 1962- GutachterIn oth Zenke, Martin GutachterIn oth Universität Rostock Grad verleihende Institution dgg Universitätsmedizin Rostock Grad verleihende Institution dgg text theses Text Hochschulschrift gw 2016 monographic XA-DE Rostock Universität publisher 2016 eng

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1 Online-Ressource The development of safe and efficient gene delivery systems is the key to the overall success of gene therapy. This work introduced a MNP-based nonviral gene delivery approach for transfection in clinically relevant cells. Moreover, the in vitro mechanism studies could explained the beneficial properties of the proposed carrier design. This work demonstrated, that proposed system could efficiently and safely transfect human bone marrow derived mesenchymal stem cells. Additionaly, the clinical perspectives of MNP-based gene therapy were discussed and evaluated in this dissertation.<eng> submitted by Evgenya Delyagina from Reinach BL, Switzerland Dissertation Universität Rostock 2017 610 http://rosdok.uni-rostock.de/resolve/urn/urn:nbn:de:gbv:28-diss2017-0038-4 Rostock : Universität, 2016

VII, 78, xii Blätter

Druck-Ausgabe (DE-627)882973460 Delyagina, Evgenya, 1986 - urn:nbn:de:gbv:28-diss2017-0038-4 979376428 rda DE-627 170327 882994220 20251224T204136.0 Converted from MARCXML to MODS version 3.8 using MARC21slim2MODS3-8_XSLT1-0.xsl (Revision 1.174 20250328) ger