Influence of polymer surface modification and specific growth factor stimulation on cellular adhesion at the implant/endothelium interface
Storm, Thilo
1974-
VerfasserIn
aut
Piechulla, Birgit
1956-
GutachterIn
oth
Hovakimyan, Marine
1977-
GutachterIn
oth
Wilhelmi, Mathias
1971-
GutachterIn
oth
Universität Rostock
Grad-verleihende Institution
dgg
Universität Rostock
Mathematisch-Naturwissenschaftliche Fakultät
Grad-verleihende Institution
dgg
text
theses
Text
Hochschulschrift
gw
2014
monographic
XA-DE
Rostock
Universität
publisher
2014
eng
1 Online-Ressource
The response of human endothelial cells (ECs) to poly(ε-caprolactone) (PCL) and eight different PCL modifications was examined in vitro. In CLSM, cell proliferation and viability testing, ECs responded best to plasma chemical activation of PCL. When ECs were additionally stimulated by VEGF, their maximum response was again seen on plasma activated PCL. Polymer precoating with matrix proteins was found to be beneficial for EC adhesion. A qPCR study of eNOS, IL-8, ICAM-1, PECAM-1 and VCAM-1 transcripts after VEGF stimulation of ECs on four modified and coated PCL surfaces was also performed.<eng>
vorgelegt von Dipl.-Biol. M.Sc. (Hons.) Thilo Storm
Dissertation Universität Rostock 2015
570
610
610
44.09
42.03
http://rosdok.uni-rostock.de/resolve/urn/urn:nbn:de:gbv:28-diss2016-0085-0
Influence of polymer surface modification and specific growth factor stimulation on cellular adhesion at the implant/endothelium interface
Rostock : Universität, 2014
Druck-Ausgabe
(DE-627)828533709
Storm, Thilo, 1974 -
urn:nbn:de:gbv:28-diss2016-0085-0
rda
DE-627
160811
865476136
20251224T202432.0
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