Molecular, immunological and genetic studies on murine autoimmune pancreatitis
Asghari, Farahnaz
1978-
aut
text
theses
Text
Hochschulschrift
gw
2015
monographic
XA-DE
2014 [erschienen] 2015
eng
text/html
application/pdf
Online-Ressource Ill., graph. Darst.
To identify susceptible regions of the genome(quantitative trait loci; QTLs)controlling Autoimmune pancreatitis in a mouse model of the disease, we established an advanced intercross line originating from three inbred mouse strains: MRL/MpJ,BXD2,NZM and wild derived strain Cast. The fourth generation of outbred intercross mice was characterized phenotypically by scoring histopathological changes of the pancreas and genotyped (Illumina, USA).Five QTLs, regulating the severity of AIP, were identified, which mapped to chromosomes 2,4,5 and 6(with Logarithmic P values varied from 3.2 to 5.4).
vorgelegt von: Farahnaz Asghari
Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2015
610
44.87
42.13
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2015-0189-6
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2015-0189-6&pdf
http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2015-0189-6
Molecular, immunological and genetic studies on murine autoimmune pancreatitis
2015
(DE-627)836209966
Asghari, Farahnaz, 1978 -
urn:nbn:de:gbv:28-diss2015-0189-6
935976830
rakwb
DE-627
151208
84238586X
20230427T073803.0
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