Transcriptional responses to radiation exposure facilitate the discovery of biomarkers functioning as radiation biodosimeters
Strunz, Sonja
1981-
aut
text
theses
Text
Hochschulschrift
gw
2013
monographic
XA-DE
2013
eng
text/html
application/pdf
Online-Ressource Ill., graph. Darst.
The development of new methods for a retrospective quantification of the radiation dose of exposed individuals is of widespread interest. To this end, I developed a computational framework for biomarker discovery and radiation dose prediction and successfully identified gene signatures with which low and medium to high radiation doses can be accurately quantified. To enhance our understanding of the radiation-induced transcriptional response, I additionally analyzed microarray data of human PBLs after ex vivo gamma-irradiation and characterized affected functional processes and pathways.
vorgelegt von Sonja Strunz, geb. Boldt
Rostock, Univ., Fak. für Informatik u. Elektrotechnik, Diss., 2014
610
WC 7700
44.64
42.11
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0136-2
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0136-2&pdf
http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2014-0136-2
Transcriptional responses to radiation exposure facilitate the discovery of biomarkers functioning as radiation biodosimeters
2013
(DE-627)793128501
Strunz, Sonja, 1981 -
urn:nbn:de:gbv:28-diss2014-0136-2
935595132
rakwb
DE-627
140909
796438269
20230427T093357.0
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