A
systems biology approach to unravel the cellular function of microRNAs
Lai, Xin
1983-
aut
text
theses
Text
Hochschulschrift
gw
2012
monographic
XA-DE
[2012]
eng
text/html
application/pdf
Online-Ressource Ill., graph. Darst.
The systems biology approach, combining biological data with mathematical modelling, provides the means to elucidate the role of miRNAs in signalling pathways and gene regulatory networks. The approach is characterised by a cyclic process, including biological network construction, mathematical modelling, simulation and experimental validation. Using this approach, I first investigate the regulatory role of miR-34a in a signalling pathway. Second, the investigation of the regulation of a miRNA target hub by multiple and cooperative miRNAs is presented.
vorgelegt von Xin Lai
Enth. Poster
Rostock, Univ., Fak. für Informatik und Elektrotechnik, Diss., 2012
WD 9200
42.11
42.13
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0077-5
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0077-5&pdf
http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2014-0077-5
A systems biology approach to unravel the cellular function of microRNAs
2012
(DE-627)739804294
Lai, Xin, 1983 -
urn:nbn:de:gbv:28-diss2014-0077-5
935383803
rakwb
DE-627
140408
782487505
20210707T123616.0
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