The
impact of tumor necrosis factor on osteogenic differentiation of human adipose tissue-derived stem cells in vitro
Salamon, Achim
1979-
aut
text
theses
Text
Hochschulschrift
gw
2012
monographic
XA-DE
2012
eng
text/html
application/pdf
Online-Ressource Ill., graph. Darst.
Chronic inflammatory diseases are characterized by elevated levels of tumor necrosis factor (TNF) and decreasing bone mineral density. TNF promotes differentiation of bone resorbing osteoclasts from their hematopoietic precursors. Its impact on differentiation of mesenchymal precursors of bone forming osteoblasts isolated from adipose (ASC) was largely unknown. I found that TNF did neither induce osteoblastic differentiation of ASC nor exhibited an impact on osteoblastic differentiation in vitro. Thus, TNF mediates osteolysis in vivo presumably mainly by its pro-osteoclastogenic effect.
vorgelegt von Achim Salamon
Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2012
42.15
42.13
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0040-8
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0040-8&pdf
http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2014-0040-8
The impact of tumor necrosis factor on osteogenic differentiation of human adipose tissue-derived stem cells in vitro
2012
Druck-Ausgabe
(DE-627)735076391
Salamon, Achim, 1979 -
urn:nbn:de:gbv:28-diss2014-0040-8
935280486
rakwb
DE-627
140207
778072312
20240719T051733.0
Converted from MARCXML to MODS version 3.8 using MARC21slim2MODS3-8_XSLT1-0.xsl
(Revision 1.174 20250328)
ger