Expression of and immune responses to leukemia antigens in patients with hematological malignancies
Casalegno Garduño, Rosaely
1982-
aut
text
theses
Text
Hochschulschrift
gw
2011
monographic
XA-DE
2011
eng
text/html
application/pdf
Online-Ressource graph. Darst.
Leukemia cells are characterized by differentially expressed leukemia-associated antigens (LAAs). We wondered whether the expression of the LAAs WT1 and RHAMM as well as the T cellular immune response to these LAAs correlated with the clinical outcome of patients suffering from leukemia. We investigated the expression of WT1 and RHAMM at RNA level using qPCR before and after treatment. We concluded that WT1 is a suitable marker for MRD after allogeneic SCT and that a WT1-specific T cell response might contribute to the maintenance of CR.
Rosaely Casalegno Garduño
Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2012
610
44.81
44.86
42.13
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0153-1
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0153-1&pdf
http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2013-0153-1
Expression of and immune responses to leukemia antigens in patients with hematological malignancies
2011
Druck-Ausgabe
(DE-627)723742987
Casalegno Garduño, Rosaely, 1982 -
urn:nbn:de:gbv:28-diss2013-0153-1
935175871
rakwb
DE-627
131128
772632693
20240719T015850.0
Converted from MARCXML to MODS version 3.8 using MARC21slim2MODS3-8_XSLT1-0.xsl
(Revision 1.174 20250328)
ger