Patient-individual models of gliomas
establishment, characterization and applications
Mullins, Christina Susanne
1984-
aut
text
theses
Text
Hochschulschrift
gw
2013
monographic
XA-DE
2013
eng
text/html
application/pdf
Online-Ressource Ill., graph. Darst.
Glioblastomas are the most common and aggressive brain tumors. The aim was establishing tumor models from individual patients (in vitro and in vivo). Modeling was successful from fresh and of note also from vitally frozen patient tumors. The models were characterized in direct comparison to the original tumors. Molecular features as mutations, amplifications and epigenetic alterations were highly maintained. Extensive drug sensitivity screens were performed. These well-defined patient individual models are ideal for establishment of individualized therapies and even immunological strategies.
vorgelegt von Christina Susanne Mullins
Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2013
44.81
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0132-4
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0132-4&pdf
http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2013-0132-4
Patient-individual models of gliomas
2013
Druck-Ausgabe
(DE-627)766723720
Mullins, Christina Susanne, 1984 -
urn:nbn:de:gbv:28-diss2013-0132-4
935145019
rakwb
DE-627
131017
77007698X
20240719T000851.0
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