KCNQ channel opening as a powerful mechanism for vasodilation
Zhuravleva, Nadezda
1984-
aut
text
theses
Text
Hochschulschrift
gw
2011
monographic
XA-DE
2011
eng
text/html
application/pdf
Online-Ressource Ill., graph. Darst.
KCNQ channels were recently found in the vascular system. We have tested the hypothesis that KCNQ channels are powerful targets for relaxation of small systemic and pulmonary arteries. In rat Gracilis arteries we found mRNA expression for KCNQ1, KCNQ3, KCNQ4 and KCNQ5 channels. We found that KCNQ channels mediate vessel relaxation induced by experimental modulators in systemic and pulmonary circulation, in normo- and hypertensive model. Conclusion: KCNQ channels could be powerful targets for vessel relaxation, also in pathological hypertensive conditions.
presented by Nadezda Zhuravleva
Rostock, Univ., Med. Fak., Diss., 2012
42.17
44.37
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2012-0095-9
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2012-0095-9&pdf
http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2012-0095-9
KCNQ channel opening as a powerful mechanism for vasodilation
2011
Druck-Ausgabe
(DE-627)716257807
Zhuravleva, Nadezda, 1984 -
urn:nbn:de:gbv:28-diss2012-0095-9
934849389
rakwb
DE-627
121029
72880977X
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