A
systems biology approach to dynamic modelling of the AMP-activated kinase pathway
Frey, Simone
1980-
aut
text
theses
Text
Hochschulschrift
gw
2011
monographic
XA-DE
2011
eng
text/html
application/pdf
Online-Ressource graph. Darst.
A systems biology approach is used to investigate a key regulator of energy sensing, the AMPK/ Snf1 pathway. Therefore, a stimulus is derived considering transmembrane glucose transport. Fluorescent microscopy data of Mig1, a Snf1 pathway component, were processed through a mathematical approach. The data were compared to simulations of alternative network structures suggested to underlie the Snf1 pathway. Certain structures could be excluded. Besides, applying quantitative measures showed that the design of a MAPK pathway is favourable for the transmission of fast signals with short duration.
vorgelegt von Simone Frey
Rostock, Univ., Fak. für Informatik und Elektrotechnik, Diss., 2011
42.15
42.13
44.33
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2011-0135-1
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2011-0135-1&pdf
http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2011-0135-1
A systems biology approach to dynamic modelling of the AMP-activated kinase pathway
2011
Druck-Ausgabe
(DE-627)66475368X
Frey, Simone, 1980 -
urn:nbn:de:gbv:28-diss2011-0135-1
839115538
rakwb
DE-627
111110
671886061
20240712T074838.0
Converted from MARCXML to MODS version 3.8 using MARC21slim2MODS3-8_XSLT1-0.xsl
(Revision 1.174 20250328)
ger