In vitro and in vivo characterization of neural progenitor cells as putative candidates for experimental studies and clinical trials in cell replacement therapy for neurodegenerative diseases
Hovakimyan, Marine
1977-
aut
text
theses
Text
Hochschulschrift
gw
2008
monographic
XA-DE
2008
eng
text/html
application/pdf
Online-Ressource Ill., graph. Darst.
Fetal conditionally immortalized striatal cells ST14A and human mesencephalic neural progenitor cells (NPCs) were studied with respect to proliferation and differentiation in in vitro experiments. In in vivo experiments, human NPCs were investigated after transplantation into neonatal and adult hemiparkinsonian rat striatum. The survival, migration and dopaminergic (DAergic) differentiation of human NPCs in the host brain was investigated. Improvement in lesion-induced motor impairment has been demonstrated in both groups of hemiparkinsonian rats, independently from DA-ergic differentiation.
vorgelegt von Marine Hovakimyan
Enth. 2 Beitr. aus Ztschr
Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2009
610
42.63
42.13
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0119-0
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0119-0&pdf
http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2009-0119-0
In vitro and in vivo characterization of neural progenitor cells as putative candidates for experimental studies and clinical trials in cell replacement therapy for neurodegenerative diseases
2008
Druck-Ausgabe
(DE-627)603442528
Hovakimyan, Marine, 1977 -
urn:nbn:de:gbv:28-diss2009-0119-0
455627820
rakwb
DE-627
090715
604745575
20240710T021443.0
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