Synthesis of biologically active N-heterocycles and amines via catalytic hydroamination of alkynes
Krüger, Karolin
1981-
aut
text
theses
Text
Hochschulschrift
gw
2008
monographic
XA-DE
2008
eng
Online-Ressource graph. Darst.
This thesis presents new syntheses of N-heterocycles and amines. Building up on our prior studies in titanium-catalyzed hydroamination of alkynes we discovered zinc salts as new hydroamination catalysts. Zinc chloride and zinc triflate were successfully applied in the intermolecular hydroamination of terminal alkynes for the synthesis of various substituted indole derivatives, pyrazolines and pyrazoles, pyridazinones as well as amines. Additional functionalization reactions on special synthesized indole structures lead to pharmaceutically and biologically interesting substances.
Karolin Krüger
Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2008
540
35.49
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2008-0096-0
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2008-0096-0&pdf
http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2008-0096-0
Synthesis of biologically active N-heterocycles and amines via catalytic hydroamination of alkynes
2008
Druck-Ausgabe
(DE-627)584537824
Krüger, Karolin, 1981 -
urn:nbn:de:gbv:28-diss2008-0096-0
301996939
rakwb
DE-627
081117
585095019
20240710T001816.0
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