New strategies for the optimisation of N-Acetylneuraminic acid synthesis
Zimmermann, Vera
1979-
aut
text
theses
Text
Hochschulschrift
gw
2008
monographic
XA-DE
2008
eng
Online-Ressource graph. Darst.
A model describing the complete enzyme catalysed synthesis of N acetylneuraminic acid (Neu5Ac is presented. The model is expedient to predict the reaction course for various conditions and therefore to calculate reaction times and yields. Using the model, an optimisation of reaction conditions in consideration of different targets was performed. Furthermore, a new method for the purification of Neu5Ac was developed. For the extraction a two step mechanism was assumed. A kinetic model was developed and combined with the model for reaction to simulate the integration of reaction and extraction.
Vera Zimmermann
Enth. Beitr. aus versch. Ztschr
Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2008
660
58.29
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2008-0079-5
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2008-0079-5&pdf
http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2008-0079-5
New strategies for the optimisation of N-Acetylneuraminic acid synthesis
2008
Druck-Ausgabe
(DE-627)573450099
Zimmermann, Vera, 1979 -
urn:nbn:de:gbv:28-diss2008-0079-5
314777663
rakwb
DE-627
080904
576922498
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