The
influence of receptor-ligand interactions on gene expression and phagosome functions in mouse macrophages
Hoffmann, Eik
1976-
aut
text
theses
Text
Hochschulschrift
gw
2007
monographic
XA-DE
2007
eng
Online-Ressource Ill., graph. Darst.
Phagocytosis, the cellular uptake of particles and pathogens, is an essential function of the innate immune response. In this study, latex beads conjugated to immunoglobulin G, bacterial lipopolysaccharides, mannan or avidin were used to induce the internalization via different phagocytic receptors. Analysis of uptake and maturation of phagosomes, their proteomes as well as of macrophage gene expression during phagocytosis demonstrated that receptor-ligand interactions at the cell surface trigger a specfic signaling 'signature', which contributes to the intracellular fate of phagosomes.
vorgelegt von Eik Hoffmann
Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2008
570
42.15
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2008-0050-9
http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2008-0050-9&pdf
http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2008-0050-9
The influence of receptor-ligand interactions on gene expression and phagosome functions in mouse macrophages
2007
Druck-Ausgabe
(DE-627)568774183
Hoffmann, Eik, 1976 -
urn:nbn:de:gbv:28-diss2008-0050-9
320540864
rakwb
DE-627
080627
570661501
20240709T234123.0
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