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    <title>Fast simultaneous angle, wedge, and beam intensity optimization in inverse radiotherapy planning</title>
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  <abstract type="Summary">We present a new fast radiotherapy planning algorithm which determines approximatively optimal gantry and table angles, kinds of wedges, leaf positions and intensities simultaneously in a global way. Other parameters are optimized only independently of each other. The algorithm uses an elaborate field management and field reduction. Beam intensities are determined via a variant of a projected Newton method of Bertsekas. The objective function is a standard piecewise quadratic penalty function, but it is built with efficient upper bounds which are calculated during the optimization process. Instead of pencil beams, basic leaf positions are included. The algorithm is implemented in the new beam modelling and dose optimization module Homo OptiS.&lt;eng&gt;</abstract>
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  <note type="statement of responsibility">Konrad Engel, Eckhard Tabbert</note>
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      <title>Preprints aus dem Institut für Mathematik</title>
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  <identifier type="doi">10.18453/rosdok_id00005908</identifier>
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