Correlations of clinical and cognitive characteristics with neuroimaging in patients with amyotrophic lateral sclerosis (ALS) and primary lateral sclerosis (PLS)
Lehto, Annaliis
1996-
VerfasserIn
aut
Prudlo, Johannes
AkademischeR BetreuerIn
dgs
Teipel, Stefan
1970-
AkademischeR BetreuerIn
dgs
Bede, Peter
AkademischeR BetreuerIn
dgs
Universität Rostock
Grad-verleihende Institution
dgg
Universitätsmedizin Rostock
Grad-verleihende Institution
dgg
text
theses
Text
Hochschulschrift
gw
2025
monographic
XA-DE
Rostock
Universität Rostock
publisher
21.05.2025
Rostock
Universitätsbibliothek Rostock
distributor
eng
1 Online-Ressource (67 Seiten) Illustrationen, Diagramme
The aim of this dissertation was to investigate brain structure and glucose metabolism changes in amyotrophic lateral sclerosis (ALS) and primary lateral sclerosis (PLS) in order to more accurately describe their correlations with patients’ motoric, cognitive or behavioural characteristics. The findings from the studies presented here illuminate multiple aspects of heterogeneity among patients with ALS and PLS in addition to improving our understanding of the neuroimaging correlates of specific phenotypic characteristics in those patient groups.<eng>
Open Access
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vorgelegt von Annaliis Lehto
Enthält Zeitschriftenartikel
Zeitschriftennachweis: Study I - Lehto A, Schumacher J, Kasper E, Teipel S, Hermann A, Kurth J, Krause B and Prudlo J (2024) Cerebral glucose metabolic correlates of cognitive and behavioural impairments in amyotrophic lateral sclerosis. Journal of Neurology 271: 5290-5300. https://doi.org/10.1007/s00415-024-12388-z ; Study II - Lehto A, Schumacher J, Kasper E, Teipel S, Hermann A and Prudlo J (2024) Loss of the ipsilateral silent period in amyotrophic lateral sclerosis is associated with reduced white matter integrity in the motor section of the corpus callosum. Journal of Neurological Sciences 466:123267. https://doi.org/10.1016/j.jns.2024.123267 ; Study III - Lehto A, Schumacher J, Kurth J, Krause B, Kasper E, Teipel S and Prudlo J (2025) Inconsistent primary motor cortex glucose hypometabolism in primary lateral sclerosis. Journal of Neurology 272, 410. https://doi.org/10.1007/s00415-025-13089-x
GutachterInnen: Johannes Prudlo (Universitätsmedizin Rostock) ; Stefan Teipel (Universitätsmedizin Rostock) ; Peter Bede (Trinity College Dublin)
Dissertation Universität Rostock 2026 Kumulative Dissertation
150
610
https://purl.uni-rostock.de/rosdok/id00005757
Correlations of clinical and cognitive characteristics with neuroimaging in patients with amyotrophic lateral sclerosis (ALS) and primary lateral sclerosis (PLS)
Rostock : Universität Rostock, 2025
Druck-Ausgabe
(DE-627)1981971602
Lehto, Annaliis, 1996 -
urn:nbn:de:gbv:28-rosdok_id00005757-5
10.18453/rosdok_id00005757
1611896326
rda
DE-627
260817
198197105X
20260817T172826.0
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