<?xml version="1.0" encoding="UTF-8"?>
<mods xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.loc.gov/mods/v3" version="3.8" xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-8.xsd">
  <titleInfo>
    <title>Non-biological liver support – improved</title>
  </titleInfo>
  <name type="personal" usage="primary">
    <namePart>Dominik, Adrian</namePart>
    <namePart type="date">1986-</namePart>
    <role>
      <roleTerm type="text">VerfasserIn</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">aut</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Stange, Jan</namePart>
    <namePart type="date">1965-</namePart>
    <role>
      <roleTerm type="text">AkademischeR BetreuerIn</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">dgs</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Lamprecht, Georg</namePart>
    <role>
      <roleTerm type="text">AkademischeR BetreuerIn</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">dgs</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Haller, Hermann</namePart>
    <namePart type="date">1953-</namePart>
    <role>
      <roleTerm type="text">AkademischeR BetreuerIn</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">dgs</roleTerm>
    </role>
  </name>
  <name type="corporate">
    <namePart>Universität Rostock</namePart>
    <role>
      <roleTerm type="text">Grad-verleihende Institution</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">dgg</roleTerm>
    </role>
  </name>
  <name type="corporate">
    <namePart>Universitätsmedizin Rostock</namePart>
    <role>
      <roleTerm type="text">Grad-verleihende Institution</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">dgg</roleTerm>
    </role>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marcgt">theses</genre>
  <genre authority="rdacontent">Text</genre>
  <genre authority="gnd-content">Hochschulschrift</genre>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">gw</placeTerm>
    </place>
    <dateIssued encoding="marc">2020</dateIssued>
    <issuance>monographic</issuance>
    <place>
      <placeTerm type="code" authority="iso3166">XA-DE</placeTerm>
    </place>
  </originInfo>
  <originInfo eventType="publication">
    <place>
      <placeTerm type="text">Rostock</placeTerm>
    </place>
    <agent>
      <namePart>Universität Rostock</namePart>
      <role>
        <roleTerm>publisher</roleTerm>
      </role>
    </agent>
    <dateIssued>2020</dateIssued>
  </originInfo>
  <originInfo eventType="distribution">
    <place>
      <placeTerm type="text">Rostock</placeTerm>
    </place>
    <agent>
      <namePart>Universitätsbibliothek Rostock</namePart>
      <role>
        <roleTerm>distributor</roleTerm>
      </role>
    </agent>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="marccategory">electronic resource</form>
    <form authority="marcsmd">remote</form>
    <form type="media" authority="rdamedia">Computermedien</form>
    <form type="carrier" authority="rdacarrier">Online-Ressource</form>
    <extent>1 Online-Ressource (ii, 32 Seiten) Illustrationen, Diagramme</extent>
  </physicalDescription>
  <abstract type="Summary">This dissertation examines how non-biological liver support systems can be improved for patients with acute or acute-on-chronic liver failure. It focuses on albumin dialysis, which removes toxins from the blood, and compares newer membranes and sorbents with the established MARS system. The main findings are that larger-pore membranes can improve removal of some albumin-bound toxins and certain cytokines, and that a newly developed micro-charcoal adsorbent performed better than standard MARS adsorbents by increasing albumin binding capacity and removing toxins more effectively.&lt;eng&gt;</abstract>
  <abstract type="Summary">Diese Dissertation untersucht, wie nicht-biologische Leberunterstützungssysteme für Patientinnen und Patienten mit akutem oder akut-auf-chronischem Leberversagen verbessert werden können. Im Mittelpunkt steht die Albumindialyse, mit der Toxine aus dem Blut entfernt werden, wobei neuere Membranen und Adsorber mit dem etablierten MARS-System verglichen werden. Die Ergebnisse zeigen, dass Membranen mit größeren Poren und der neue Aktivkohleadsorber die Entfernung albumingebundener Toxine und Zytokine verbessern können.&lt;ger&gt;</abstract>
  <accessCondition type="restriction on access" valueURI="http://purl.org/coar/access_right/c_abf2">Open Access</accessCondition>
  <accessCondition type="use and reproduction" authority="rs" valueURI="http://rightsstatements.org/vocab/InC/1.0/">Urheberrechtsschutz 1.0</accessCondition>
  <note type="statement of responsibility">vorgelegt von Adrian Dominik</note>
  <note>Der Volltext der Zeitschriftenartikel ist nur in der Druckausgabe vorhanden</note>
  <note>GutachterInnen: Jan Stange (Universitätsmedizin Rostock) ; Georg Lamprecht (Universitätsmedizin Rostock) ; Hermann Haller (Universitätsmedizin Hannover)</note>
  <note type="thesis">Dissertation Universität Rostock 2022 Kumulative Dissertation</note>
  <classification authority="ddc">500</classification>
  <classification authority="ddc">600</classification>
  <classification authority="ddc">610</classification>
  <location>
    <url displayLabel="electronic resource" usage="primary display" note="kostenfrei">https://purl.uni-rostock.de/rosdok/id00005485</url>
  </location>
  <relatedItem type="otherFormat" otherType="Erscheint auch als" displayLabel="Erscheint auch als">
    <titleInfo>
      <title>Non-biological liver support – improved</title>
    </titleInfo>
    <originInfo>
      <publisher>Rostock : Universität Rostock, 2019</publisher>
    </originInfo>
    <physicalDescription>
      <form>1 Band (verschiedene Seitenzählungen)</form>
    </physicalDescription>
    <note>Druck-Ausgabe</note>
    <identifier type="local">(DE-627)1970771933</identifier>
    <name>
      <namePart>Dominik, Adrian, 1986 - </namePart>
    </name>
  </relatedItem>
  <identifier type="urn">urn:nbn:de:gbv:28-rosdok_id00005485-2</identifier>
  <identifier type="doi">10.18453/rosdok_id00005485</identifier>
  <identifier type="oclc">1589315487</identifier>
  <recordInfo>
    <descriptionStandard>rda</descriptionStandard>
    <recordContentSource authority="marcorg">DE-627</recordContentSource>
    <recordCreationDate encoding="marc">260508</recordCreationDate>
    <recordIdentifier source="DE-627">1970767383</recordIdentifier>
    <recordChangeDate encoding="iso8601">20260508T114019.0</recordChangeDate>
    <recordOrigin>Converted from MARCXML to MODS version 3.8 using MARC21slim2MODS3-8_XSLT1-0.xsl
				(Revision 1.174 20250328)</recordOrigin>
    <languageOfCataloging>
      <languageTerm authority="iso639-2b" type="code">ger</languageTerm>
    </languageOfCataloging>
  </recordInfo>
</mods>
