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  <abstract type="Summary">Im Pilocarpin-Rattenmodell der Temporallappenepilepsie wurde untersucht, ob eine frühe Behandlung mit Mycophenolatmofetil (MMF) nach einem Status epilepticus die Anfallshäufigkeit beeinflusst. Die Video-EEG-Auswertung zeigte keine signifikante Reduktion der Anfallshäufigkeit in der MMF-Gruppe im Vergleich zur Placebokontrolle. Allerdings war die Anfallsaktivität in der MMF-Gruppe weniger variabel, was auf eine mögliche immunologische Modulation des Krankheitsverlaufs hindeutet.&lt;ger&gt;</abstract>
  <abstract type="Summary">The pilocarpine rat model of temporal lobe epilepsy was used to investigate whether early treatment with mycophenolate mofetil (MMF) after status epilepticus influences seizure frequency. The video-EEG analysis showed no significant reduction in seizure frequency in the MMF group compared to the placebo control. However, seizure activity was less variable in the MMF group, indicating a possible immunological modulation of the course of the disease.&lt;eng&gt;</abstract>
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  <note type="statement of responsibility">vorgelegt von Franziska Frenck</note>
  <note>GutachterInnen: Timo Kirschstein (Universitätsmedizin Rostock) ; Volkmar Leßmann (Universitätsmedizin Magdeburg) ; Astrid Bertsche (Universitätsmedizin Greifswald)</note>
  <note type="thesis">Dissertation Universität Rostock 2025</note>
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      <title>Langzeit-Video-EEG-Analysen von epileptischen Ratten unter Mycophenolatmofetil-Therapie</title>
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      <publisher>Rostock : Universität Rostock, 2024</publisher>
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      <namePart>Frenck, Franziska, 1991 - </namePart>
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  <identifier type="urn">urn:nbn:de:gbv:28-rosdok_id00005269-0</identifier>
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