Gender-specific impact of direct-coupled alternating electric fields on human chondrocytes
Song, Zezhong
1989-
VerfasserIn
aut
Bader, Rainer
1965-
AkademischeR BetreuerIn
dgs
Bertrand, Jessica
1978-
AkademischeR BetreuerIn
dgs
Peters, Kirsten
1966-
AkademischeR BetreuerIn
dgs
Universität Rostock
Grad-verleihende Institution
dgg
Universitätsmedizin Rostock
Grad-verleihende Institution
dgg
text
theses
Text
Hochschulschrift
gw
2024
monographic
XA-DE
Rostock
Universität Rostock
publisher
June 2024
Rostock
Universitätsbibliothek Rostock
distributor
eng
application/pdf
1 Online-Ressource (V, 87 Seiten) Illustrationen, Diagramme
In cell-based therapy for cartilage repair, preventing fibrocartilage formation due to dedifferentiation is crucial. This study examined how alternating electric fields affect the redifferentiation of human chondrocytes from male and female donors. Stimulation at 15–20 V/m increased the Col2/Col1 ratio and promoted rounded morphology, indicating enhanced redifferentiation. Meanwhile, female chondrocytes showed more collagen 1 production and fibroblast-like shape. These results suggest male chondrocytes showed higher tendency towards redifferentiation in response to electrical stimulation.<eng>
Open Access
Urheberrechtsschutz 1.0
vorgelegt von Zezhong Song
GutachterInnen: Rainer Bader (Forschungslabor für Biomechanik und Implantattechnologie, Universität Rostock) ; Jessica Bertrand (Orthopädische Universitätsklinik mit Endoprothetikzentrum, Universitätsklinikum Magdeburg) ; Kirsten Peters (Center for Medical Research (ZEMFO), Institute of Cell Biology, Universität Rostock)
Dissertation Universität Rostock 2025
570
610
616.7
610
https://purl.uni-rostock.de/rosdok/id00005205
https://doi.org/10.18453/rosdok_id00005205
https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00005205-6
https://d-nb.info/1394543700/34
Gender-specific impact of direct-coupled alternating electric fields on human chondrocytes
Rostock : Universität Rostock, 2024
Druck-Ausgabe
(DE-627)1966685114
Song, Zezhong, 1989 -
urn:nbn:de:gbv:28-rosdok_id00005205-6
10.18453/rosdok_id00005205
1579972014
rda
DE-627
260319
1966684843
20260409T061624.0
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