Evaluating in vitro toxicity of flavors in alternative nicotine delivery systems utilizing different in vitro testing strategies
Rinaldi, Selina
1992-
VerfasserIn
aut
Zimmermann, Ralf
1963-
AkademischeR BetreuerIn
dgs
Schwerdtle, Tanja
1975-
AkademischeR BetreuerIn
dgs
Universität Rostock
Grad-verleihende Institution
dgg
Universität Rostock
Mathematisch-Naturwissenschaftliche Fakultät
Grad-verleihende Institution
dgg
text
theses
Text
Hochschulschrift
gw
2025
monographic
XA-DE
Rostock
Universität Rostock
publisher
March 2025
Rostock
Universitätsbibliothek Rostock
distributor
eng
application/pdf
1 Online-Ressource (XIII, 53 Seiten) Illustrationen, Diagramme
The respiratory and local health effects of flavors in alternative nicotine delivery systems (ANDS) are not well understood. This dissertation aimed to develop an in vitro risk assessment strategy for ANDS flavors and identify oral nicotine pouch (ONP) ingredients. Further, the impinger method was optimized for collecting flavored aerosols. Based on the results, a tiered testing approach is advised using submerged and Air-Liquid Interface cell models. Further, standardized testing guidelines for flavoring compounds in emerging ANDS are needed for comprehensive safety assessments.<eng>
Open Access
Urheberrechtsschutz 1.0
vorgelegt von Selina Rinaldi
Der Volltext der Zeitschriftenartikel ist nur in der Druckausgabe vorhanden
GutachterInnen: Ralf Zimmermann (University of Rostock, Institute of Chemistry) ; Tanja Schwerdtle (Max Rubner-Institut and University of Potsdam, Institute of Nutritional Science, Department of Food Chemistry)
Dissertation Universität Rostock 2025 Kumulative Dissertation
500
540
570
615.9
610
https://purl.uni-rostock.de/rosdok/id00004874
https://doi.org/10.18453/rosdok_id00004874
https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004874-8
https://d-nb.info/1372071903/34
Evaluating in vitro toxicity of flavors in alternative nicotine delivery systems utilizing different in vitro testing strategies
Rostock : Universität Rostock, 2025
Druck-Ausgabe
(DE-627)1931306168
Rinaldi, Selina, 1992 -
urn:nbn:de:gbv:28-rosdok_id00004874-8
10.18453/rosdok_id00004874
1528175581
rda
DE-627
250718
1931303371
20251227T185819.0
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