Phosphoproteome analysis of the near-haploid cell line HAP1 reveals phosphorylation events originating from PDZ-binding kinase/T-LAK cell-originated protein kinase (PBK/TOPK)
Albony, Hasan
1981-
VerfasserIn
aut
Thiesen, Hans-Jürgen
1956-
AkademischeR BetreuerIn
dgs
Gerner, Christopher
AkademischeR BetreuerIn
dgs
Murua Escobar, Hugo Istvan
1973-
AkademischeR BetreuerIn
dgs
Universität Rostock
Grad-verleihende Institution
dgg
Universitätsmedizin Rostock
Grad-verleihende Institution
dgg
text
theses
Text
Hochschulschrift
gw
2021
monographic
XA-DE
Rostock
Universität Rostock
publisher
29.04.2021
Rostock
Universitätsbibliothek Rostock
distributor
eng
application/pdf
1 Online-Ressource (III, 126 Seiten) Illustrationen, Diagramme
PBK is a serine/threonine kinase. During mitosis, PBK phosphorylates the inter-zinc finger linker sequence (TGEKP) of hundreds of C2H2 zinc finger proteins and liberates these transcription factors from the condensing chromatin. This study aimed to investigate PBK-dependent phosphorylation events by analyzing the phosphoproteome of both wild and PBK knockout HAP1 cells. The analysis identified candidates belong to DNA- and RNA binding proteins (ADNP and FUBP1) or dynamic regulators of cell organelles (MARCKS and PGRMC1).<eng>
Open Access
Urheberrechtsschutz 1.0
vorgelegt von Hasan Albony
GutachterInnen: Hans-Jürgen Thiesen (Institut für Immunologie, Universität Rostock) ; Christopher Gerner (Fakultät für Chemie, Universität Wien) ; Hugo Murua Escobar (Medizinische Klinik III, Universität Rostock)
Dissertation Universität Rostock 2022
570
571.84
570
XD 2904
XD 3304
44.45
https://purl.uni-rostock.de/rosdok/id00004478
https://doi.org/10.18453/rosdok_id00004478
https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004478-9
https://d-nb.info/1313002321/34
Phosphoproteome analysis of the near-haploid cell line HAP1 reveals phosphorylation events originating from PDZ-binding kinase/T-LAK cell-originated protein kinase (PBK/TOPK)
Rostock : Universität Rostock, 2021
Druck-Ausgabe
(DE-627)1832389812
Albony, Hasan, 1981 -
urn:nbn:de:gbv:28-rosdok_id00004478-9
10.18453/rosdok_id00004478
1412000751
rda
DE-627
231206
1872125352
20251226T213128.0
Converted from MARCXML to MODS version 3.8 using MARC21slim2MODS3-8_XSLT1-0.xsl
(Revision 1.174 20250328)
ger