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    <title>Untersuchungen zur Hemmung der Biofilmbildung anaerober Mikroorganismen am Beispiel von Clostridioides difficile</title>
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  <abstract type="Summary">Clostridioides difficile ist ein sporenbildender, anaerober und biofilmbildender Mikroorganismus. Aufgrund der vermehrten Antibiotikaresistenzen wurden alternative Substanzen zur antimikrobiellen Beschichtung von Implantatoberflächen untersucht. Schistosomale Tegumentproteine zeigen antithrombotische Eigenschaften für Implantatoberflächen. Der Einfluss auf die Biofilmbildung ist nicht bekannt. Das rekombinant hergestellte Protein rSm22.6 zeigte keinen Effekt auf die Biofilmbildung. D-Aminosäuren und cis-2-Decensäure zeigten inhibierende Effekte auf Biofilme von C. difficile.&lt;ger&gt;</abstract>
  <abstract type="Summary">Clostridioides difficile is a spore-forming, anaerobic and biofilm forming microorganism. Due to increased antibiotic resistance, alternative substances for antimicrobial coating of implant surfaces have been investigated. Schistosomal tegument proteins show antithrombotic properties, which are ideal for implant surfaces. The effect on biofilm formation is not known. The recombinantly produced protein rSm22.6 showed no effect on biofilm formation. D-amino acids and cis-2-decenoic acid showed on C. difficile biofilm formation.&lt;eng&gt;</abstract>
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  <note type="statement of responsibility">vorgelegt von Julia Strübing</note>
  <note>GutachterInnen: Hubert Bahl (Universität Rostock, Institut für Biowissenschaften) ; Michael Hecker (Universität Rostock, Institut für Mikrobiologie)</note>
  <note type="thesis">Dissertation Universität Rostock 2023</note>
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    <titleInfo>
      <title>Untersuchungen zur Hemmung der Biofilmbildung anaerober Mikroorganismen am Beispiel von Clostridioides difficile</title>
    </titleInfo>
    <originInfo>
      <publisher>Rostock : Universität Rostock, 2022</publisher>
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      <namePart>Strübing, Julia, 1988 - </namePart>
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