<?xml version="1.0" encoding="UTF-8"?>
<mods xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.loc.gov/mods/v3" version="3.8" xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-8.xsd">
  <titleInfo>
    <title>Neonatale Alloimmunthrombozytopenie</title>
    <subTitle>immunologische Befunde und klinische Ausprägung</subTitle>
  </titleInfo>
  <name type="personal" usage="primary">
    <namePart>Greger, Nico</namePart>
    <namePart type="date">1980-</namePart>
    <role>
      <roleTerm type="text">VerfasserIn</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">aut</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Kiefel, Volker</namePart>
    <namePart type="date">1954-</namePart>
    <role>
      <roleTerm type="text">AkademischeR BetreuerIn</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">dgs</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Classen, Carl Friedrich</namePart>
    <namePart type="date">1962-</namePart>
    <role>
      <roleTerm type="text">AkademischeR BetreuerIn</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">dgs</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Böck, Marcus</namePart>
    <role>
      <roleTerm type="text">AkademischeR BetreuerIn</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">dgs</roleTerm>
    </role>
  </name>
  <name type="corporate">
    <namePart>Universität Rostock</namePart>
    <role>
      <roleTerm type="text">Grad-verleihende Institution</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">dgg</roleTerm>
    </role>
  </name>
  <name type="corporate">
    <namePart>Universitätsmedizin Rostock</namePart>
    <role>
      <roleTerm type="text">Grad-verleihende Institution</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">dgg</roleTerm>
    </role>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marcgt">theses</genre>
  <genre authority="rdacontent">Text</genre>
  <genre authority="gnd-content">Hochschulschrift</genre>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">gw</placeTerm>
    </place>
    <dateIssued encoding="marc">2022</dateIssued>
    <issuance>monographic</issuance>
    <place>
      <placeTerm type="code" authority="iso3166">XA-DE</placeTerm>
    </place>
  </originInfo>
  <originInfo eventType="publication">
    <place>
      <placeTerm type="text">Rostock</placeTerm>
    </place>
    <agent>
      <namePart>Universität Rostock</namePart>
      <role>
        <roleTerm>publisher</roleTerm>
      </role>
    </agent>
    <dateIssued>2022</dateIssued>
  </originInfo>
  <originInfo eventType="distribution">
    <place>
      <placeTerm type="text">Rostock</placeTerm>
    </place>
    <agent>
      <namePart>Universitätsbibliothek Rostock</namePart>
      <role>
        <roleTerm>distributor</roleTerm>
      </role>
    </agent>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">ger</languageTerm>
  </language>
  <physicalDescription>
    <form authority="marccategory">electronic resource</form>
    <form authority="marcsmd">remote</form>
    <form type="media" authority="rdamedia">Computermedien</form>
    <form type="carrier" authority="rdacarrier">Online-Ressource</form>
    <extent>1 Online-Ressource (88 Seiten) Illustrationenm, Diagramme</extent>
  </physicalDescription>
  <abstract type="Summary">Die neonatale Alloimmunthrombozytopenie (NAIT) ist eine seltene Erkrankung des Neugeborenen. In der FNAIT-Studie konnte gezeigt werden, dass im Vergleich zu historischen Daten Anti-HPA-1a weiterhin am häufigsten auftrat, Anti-HPA-5b jedoch signifikant seltener vorkam. Mütter mit nachweisbarem Anti-HPA-1a waren im Vergleich zur Normalbevölkerung signifikant seltener RhD-negativ. In der Anti-HPA-1a-Studie konnte keine Korrelation zwischen Antikörperkonzentration und neonataler Thrombozytopenie gefunden werden, jedoch zwischen Antikörperkonzentration und milden Blutungszeichen des Neugeborenen.&lt;ger&gt;</abstract>
  <abstract type="Summary">Neonatal alloimmune thrombocytopenia (NAIT) is a rare disease of the newborn. The FNAIT study showed that anti-HPA-1a is still by far the most frequently found antibody, but anti-HPA-5b was, compared to historical data, significantly less frequent. Mothers with detectable anti-HPA-1a were significantly less likely to be RhD negative compared with the normal population. In the anti-HPA-1a study, no correlation was found between antibody concentration and neonatal thrombocytopenia, but a correlation was found between antibody concentration and mild neonatal bleeding signs.&lt;eng&gt;</abstract>
  <accessCondition type="restriction on access" valueURI="http://purl.org/coar/access_right/c_abf2">Open Access</accessCondition>
  <accessCondition type="use and reproduction" authority="cc" valueURI="https://creativecommons.org/licenses/by-nc-sa/4.0/">Namensnennung - Nicht-kommerziell - Weitergabe unter gleichen Bedingungen 4.0 International</accessCondition>
  <note type="statement of responsibility">vorgelegt von Nico Greger</note>
  <note>GutachterInnen: Volker Kiefel (Institut für Transfusionsmedizin, Universitätsmedizin Rostock) ; Carl Friedrich Classen (Kinder- und Jugendklinik, Universitätsmedizin Rostock) ; Marcus Böck (Institut für Klinische Transfusionsmedizin und Hämotherapie, Universitätsklinikum Würzburg)</note>
  <note type="thesis">Dissertation Universität Rostock 2023</note>
  <classification authority="ddc">610</classification>
  <classification authority="ddc">618.92</classification>
  <classification authority="ddc">610</classification>
  <classification authority="bkl">44.67</classification>
  <classification authority="bkl">44.78</classification>
  <classification authority="bkl">44.86</classification>
  <location>
    <url displayLabel="electronic resource" usage="primary display" note="kostenfrei">http://purl.uni-rostock.de/rosdok/id00004229</url>
  </location>
  <location>
    <url displayLabel="electronic resource" note="kostenfrei">https://doi.org/10.18453/rosdok_id00004229</url>
  </location>
  <location>
    <url displayLabel="electronic resource" note="kostenfrei">https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004229-8</url>
  </location>
  <location>
    <url displayLabel="electronic resource" note="kostenfrei">https://d-nb.info/1293540684/34</url>
  </location>
  <relatedItem type="otherFormat" otherType="Erscheint auch als" displayLabel="Erscheint auch als">
    <titleInfo>
      <title>Neonatale Alloimmunthrombozytopenie</title>
    </titleInfo>
    <originInfo>
      <publisher>Rostock : Universität Rostock, 2022</publisher>
    </originInfo>
    <physicalDescription>
      <form>88 Seiten</form>
    </physicalDescription>
    <note>Druck-Ausgabe</note>
    <identifier type="local">(DE-627)1839222042</identifier>
    <name>
      <namePart>Greger, Nico, 1980 - </namePart>
    </name>
  </relatedItem>
  <identifier type="urn">urn:nbn:de:gbv:28-rosdok_id00004229-8</identifier>
  <identifier type="doi">10.18453/rosdok_id00004229</identifier>
  <identifier type="oclc">1372626661</identifier>
  <recordInfo>
    <descriptionStandard>rda</descriptionStandard>
    <recordContentSource authority="marcorg">DE-627</recordContentSource>
    <recordCreationDate encoding="marc">230315</recordCreationDate>
    <recordIdentifier source="DE-627">1839217561</recordIdentifier>
    <recordChangeDate encoding="iso8601">20251226T210015.0</recordChangeDate>
    <recordOrigin>Converted from MARCXML to MODS version 3.8 using MARC21slim2MODS3-8_XSLT1-0.xsl
				(Revision 1.174 20250328)</recordOrigin>
    <languageOfCataloging>
      <languageTerm authority="iso639-2b" type="code">ger</languageTerm>
    </languageOfCataloging>
  </recordInfo>
</mods>
